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Wellbutrin (generic name: bupropion) Less common symptoms: Buzzing or ringing in the ears, severe headache, skin reaction (rash, hives What side effects may I notice from receiving this medication? Allergic reactionsskin rash, itching, hives, swelling of the face, lips, tongue, or throat uro mp side effects itchy skin, skin rash, hives, swelling, shortness of breath, chest pain Wellbutrin XL, Wellbutrin SR, bupropion HCl, and Forfivo XL aren’t FDA-approved Bupropion In a closer examination of the effects of bupropion on negative affect, through a post hoc analysis of monotherapy treatment (bupropion versus escitalopram) in patients with MDD (n = 163), Gerra and colleagues reported that whilst response to escitalopram did not differ significantly between low- and high-negative-affect patients, bupropion was