Cyclobenzaprine: MedlinePlus Drug Information
Avoid driving or hazardous activity until you know how cyclobenzaprine will affect you. Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse. Older adults may be more sensitive to the effects of this medicine.
- If this medication upsets your stomach, take it with food or milk.
- It is not known whether this drug is excreted in human milk.
- Although not all of these side effects may occur, if they do occur they may need medical attention.
- Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Research indicates that it primarily acts within the central nervous system in the brain stem. The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome.
This enables the provider to evaluate for any potential interactions and helps them keep the patient safe. Even if it feels like the effects of cyclobenzaprine have worn off, the drug may not be completely eliminated from the body yet and could cause serious interactions with other substances. Signs of overdose include chest pain, hallucinations, vomiting, rapid heartbeat, slurred speech, difficulty breathing, and extreme drowsiness. The risk of overdose is significantly increased when Flexeril is combined with other drugs, particularly alcohol or Benzodiazepines.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at FDA-1088 or at /medwatch. If any of these effects last or get worse, tell your doctor or pharmacist promptly. In a pharmacokinetic study of sixteen subjects with hepatic impairment (15 flexeril dry mouth mild, 1 moderate per Child-Pugh score), both AUC and Cmax were approximately double the values seen in the healthy control group. Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward.
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The kidneys of older adults may not work as well as they used to. As a result, more of a drug stays in your body for longer. Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.
What special precautions should I follow?
The extended-release capsule is usually taken with or without food once a day. Do not take this drug for more than 3 weeks without talking to your doctor. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome.
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Withdrawal symptoms have been noted with the discontinuation of chronic cyclobenzaprine use. Use of a medication taper may be warranted for chronic-use patients. Your healthcare professional will be able to give you instructions on how to take your Flexeril prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.Flexeril can come in different forms and doses, so follow the specific instructions on your prescription.
Severe CNS depression may result in significantly slowed breathing, over sedation, coma, and death.3 If you are unable to stop abusing one or more substance, it’s time to seek help. Admitting your substance use has gotten out of control can save your life. Please call our 24-hour hotline listed above if you need information about treatment for addiction to Flexeril or alcohol for yourself or for a loved one. Drug interactions and warnings issued with Flexeril state that the drug “may enhance the effects of alcohol.”6 It would be unwise to misinterpret this statement as an endorsement to use this dangerous combination. Cyclobenzaprine oral tablet may cause drowsiness and dizziness.
Rinse the mouth to make sure all of the medicine have been swallowed. Do not take more of it and do not take it more often than your doctor ordered. To do so may increase the chance of serious side effects. We may receive advertising fees if you follow links to promoted online therapy websites. Get professional help from an online addiction and mental health counselor from BetterHelp.
The results suggest that cyclobenzaprine is superior to both placebo and clonazepam when added to self-care and education for the management of jaw pain upon awakening. In this study cyclobenzaprine (10mg/d) failed to significantly improve sleep in the short term but this may have been due to the relatively low dose employed. The usual dose is 5–10mg three times daily and treatment for more than 2–3 weeks is not recommended. There is also a slight risk that abuse of Cyclobenzaprine or Flexeril can lead to serotonin syndrome.